Prolactin vs Oxytocin in Breastfeeding: Comparing Their Roles

BY KATIE CLARK, IBCLC

Your body’s incredible milk-making process relies on a perfectly choreographed dance between two essential hormones: prolactin and oxytocin. Understanding how these hormones work together can make a significant difference in your breastfeeding journey, helping you feel more confident and informed about what’s happening in your body.

If you’ve ever wondered why your breasts know exactly when to make milk and when to release it, you’re about to discover the fascinating interplay between these two crucial hormones. 

As an International Board Certified Lactation Consultant, I’ve seen how this knowledge can transform a mother’s confidence in her body’s abilities.

Think of prolactin as your milk production manager and oxytocin as your delivery specialist – each has a unique but equally important role in successful breastfeeding.

In this guide, we’ll explore:

  • The distinct roles of prolactin and oxytocin
  • How these hormones work together to support breastfeeding
  • Practical ways to support healthy hormone function
  • Solutions to common hormone-related breastfeeding challenges

Whether you’re just starting your breastfeeding journey or looking to understand how breastfeeding works better, this information will help you navigate the process with greater confidence.

Understanding the Basics

What is Prolactin?

Prolactin is your body’s primary milk-making hormone. Think of it as the factory manager responsible for milk production. When your baby suckles at the breast, prolactin levels increase and remain elevated throughout the feeding session. Having appropriate prolactin levels are crucial for effective milk production.

One interesting fact about prolactin is that its levels peak during the early morning hours—specifically between 2 and 6 AM—explaining why many mothers notice fuller breasts in the morning. This is also why it’s not recommended to eliminate middle-of-the-night expressions too early.

Key Prolactin Facts:

  • Primarily responsible for milk production
  • Levels increase with breast stimulation
  • Production begins during pregnancy but is suppressed until after birth
  • Higher levels correlate with successful breastfeeding outcomes (Source)

What is Oxytocin?

Oxytocin, often called the “love hormone,” is crucial in milk release. It’s responsible for the let-down reflex, which moves milk from the milk-producing cells to your baby. However, oxytocin does more than just help with milk flow – it also promotes bonding and reduces stress during breastfeeding sessions.

Key Oxytocin Facts:

  • Triggers the let-down reflex
  • Released in a pulsatile manner during breastfeeding (Source)
  • Promotes mother-baby bonding
  • Can be affected by stress and the environment

Understanding these essential functions is crucial for recognizing potential signs of low milk supply and knowing when to seek support.

An infographic titled 'Comparing Roles and Functions of Milk-Related Hormones' featuring a balanced scale diagram comparing Prolactin and Oxytocin. On the Prolactin side (left), three characteristics are listed with corresponding icons: 'Stimulus response' (baby and hand icon), 'Peak activity early' (sunrise icon), and 'Milk production focus' (bottle with plus icon). On the Oxytocin side (right), three matching characteristics are shown: 'Multiple triggers' (baby face icon), 'Pulsatile release' (wave pattern icon), and 'Milk ejection role' (bottle with arrow icon). All icons are rendered in coral pink, and The Breastfeeding Mama logo appears at the bottom.

Comparing Key Functions

AspectProlactinOxytocin
Primary FunctionMilk productionMilk ejection
TimingPeaks 2-6 AM; remains elevated during feedingReleased in pulses during feeding
TriggerNipple stimulation, infant sucklingSuckling, baby’s cry, thinking of baby
Additional BenefitsMaintains milk supplyPromotes bonding, reduces stress

Prolactin’s Role in Detail

Prolactin works as your body’s milk production manager, and its function is quite remarkable. When your baby suckles, prolactin levels increase and begin stimulating the mammary glands to produce milk. This hormone’s effectiveness is closely tied to how frequently you breastfeed or pump.

Important: Studies show that mothers who exclusively breastfeed tend to have higher levels of both prolactin and oxytocin compared to those who supplement with formula (Source).

Here’s how prolactin works:

  • Responds to breast stimulation
  • Signals breast tissue to make milk
  • Levels naturally fluctuate throughout the day
  • Production can be affected by stress and fatigue

For more information about maintaining a healthy milk supply, check out our guide on how to increase milk supply.

Oxytocin’s Role in Detail

Oxytocin’s function extends beyond just milk ejection. This remarkable hormone creates what we call the “let-down reflex,” which is essential for your baby to receive milk effectively. Research shows that oxytocin is released in a pulsatile manner during breastfeeding (Source).

Key aspects of oxytocin’s role:

  • Contracts muscles around milk-producing cells
  • Pushes milk through the ducts
  • Promotes emotional bonding with baby
  • Helps reduce maternal stress

Understanding these roles can help you better prepare for breastfeeding your newborn baby.

How These Hormones Work Together

The relationship between prolactin and oxytocin is like a well-orchestrated symphony. While each hormone has a distinct role, their coordination makes successful breastfeeding possible.

A flowchart illustrating the 'Hormonal Sequence in Breastfeeding' with five sequential steps connected by arrows, using a gradient color scheme from yellow to purple. The sequence begins with 'Initial Trigger' (baby begins suckling), followed by 'Nerve Activation' (nerve endings in nipple activated), 'Prolactin Increase' (prolactin levels increase), 'Oxytocin Pulses' (oxytocin pulses begin), and concludes with 'Milk Flow' (milk flows and cycle continues). Each step is presented in a rectangular box with both the title and descriptive text. The Breastfeeding Mama logo appears in the bottom right corner.

The Breastfeeding Hormone Cycle:

  1. Baby begins suckling, triggering nerve endings in the nipple
  2. Prolactin levels rise, signaling milk production
  3. Oxytocin releases in pulses, triggering let-down
  4. Milk flows, reinforcing the cycle

“Both hormones are elevated during breastfeeding episodes, with oxytocin facilitating prolactin release, which supports ongoing milk production” (Source).

A professional marketing banner featuring a soft-focus background image of a mother breastfeeding her baby, her face gently turned downward. The main text reads 'Empower Your Breastfeeding Journey' in a bold, contemporary font, followed by a descriptive subtitle stating 'Join The Breastfeeding Mama community for expert advice, personalized support, and a network of moms just like you.' A prominent yellow call-to-action button displays 'Join Fuss-Free Now' at the bottom of the banner. The Breastfeeding Mama logo, featuring a teardrop-shaped icon with a mother and baby silhouette in coral pink, appears in the lower right corner

Practical Implications for Breastfeeding Mothers

Understanding how prolactin and oxytocin work together can help you optimize your breastfeeding experience. Let’s explore practical ways to support these essential hormones.

Supporting Healthy Hormone Function

Tips for Optimal Hormone Function:

  • For Prolactin:
    • Breastfeed or pump frequently, especially during night hours
    • Ensure proper latch and breast drainage
    • Consider power pumping if the supply needs a boost
  • For Oxytocin:
    • Create a calm, comfortable feeding environment
    • Practice skin-to-skin contact
    • Stay hydrated and well-nourished

For more detailed guidance on creating an optimal breastfeeding environment, visit our guide on breastfeeding station ideas.

Common Challenges and Solutions

Challenge 1: Stress Impact

Stress can affect both prolactin and oxytocin levels. Research indicates that stress-induced suppression of prolactin can particularly impact lactation (Source).

Solutions:

Challenge 2: Delayed Let-Down

Sometimes, oxytocin release may be delayed, affecting milk flow. This can happen again, due to stress, menstrual cycles, etc.

Solutions:

  • Use warm compresses before feeding
  • Practice breast massage
  • Focus on bonding with your baby during feeds – use lots of skin to skin
  • Consider the use of oxytocin spray (please work with an IBCLC if this is something you’re considering)

For more support with milk supply concerns, check out our comprehensive guide on signs of low milk supply.

Final Thoughts

Understanding the roles of prolactin and oxytocin in breastfeeding can significantly impact your confidence and success in your breastfeeding journey.

Remember that these hormones work as a team—prolactin is your milk producer, and oxytocin is your milk releaser—each playing a vital role in nourishing your baby.

Key Takeaways:

  • Prolactin and oxytocin work synergistically for successful breastfeeding
  • Regular breast stimulation helps maintain healthy hormone levels
  • A calm environment supports optimal hormone function
  • Support is available if you’re experiencing challenges

Remember that support is available if you’re experiencing any concerns about your breastfeeding journey. Consider scheduling a virtual consultation with our expert lactation consultant team member who can provide personalized guidance based on your specific situation.

For more breastfeeding support and resources, explore our comprehensive breastfeeding questions guide.

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Welcome ToThe Breastfeeding Mama

Hi! I’m Katie Clark – mom of three and International Board Certified Lactation Consultant. Over the past eight years, I’ve dedicated my life to helping thousands of breastfeeding moms around the world overcome their breastfeeding problems and find peace in their journey. I can’t wait to help you!